Copper Deficiency Glossary
Copper Depletion - Abnormally low levels of copper in the blood. Low levels of copper in the blood - In a study published in the August 2008 issue of the journal Neurology, researchers at the University of Texas Southwestern Medical Center in Dallas studied four denture-wearing patients who had developed neurological problems, all of whom were chronic and excessive users of denture adhesive cream. All four subjects had abnormally high levels of zinc in their blood, accompanied by abnormally low levels of copper. Neither of these conditions could be attributed to any alternative source. Based on the study, researchers concluded that chronic and excessive use of zinc-containing denture creams may result in copper depletion and serious neurological disease.
Copper Deficiency - A deficiency in Copper can cause many hematological manifestations, such as myelodysplasia, anemia, leukopenia (low white blood cell count) and neutropenia (low count of neutrophils, a type of white blood cell that is often called "the first line of defense" for the immune system) The deficiency in copper can cause many hematological manifestations, such as myelodysplasia, anemia, leukopenia (low white blood cell count) and neutropenia (low count of neutrophils, a type of white blood cell that is often called "the first line of defense" for the immune system).
High Levels of Zinc in the Blood - Small amounts of zinc are necessary for a healthy and balanced diet but can be toxic if ingested in large amounts. Zinc poisoning symptoms could include paralysis, numbness, pain, muscle weakness, loss of sensation, loss of balance or difficulty walking. Excess zinc in the body also causes a depletion of copper, known as hypocupremia, which can cause neurological damage, neuropathy and other complications.
The recommended daily allowance of zinc is only 11 mg/day for men and 8 mg/day for women, and the highest amount that can be safely tolerated is 40 mg/day. Researchers have found that zinc side effects from Fixodent, PoliGrip and other denture cream adhesives can cause users to be exposed to as much as 330 mg of zinc per day.
Although zinc levels may return to normal after Fixodent or PoliGrip are stopped, the damage caused by long-term use of the products can be permanent, leaving users with painful and debilitating injuries that may result in the need for a wheelchair, walker or cane.
Many doctors remain unaware of the potential connection between the use of denture cream and zinc poisoning, therefore the generalized complaints associated with side effects of denture cream could go undiagnosed or be mistakenly attributed to a different cause.
Hyperzincuria - is an excess of zinc in the blood that can be caused by the use of denture cream containing zinc. It can lead to anemia and neurological deficiencies that can eventually develop into a lack of sensation and control in your limbs. Hypocupremia - abnormally low levels of copper in the blood, A study conducted by researchers at the University of Texas Southwestern Medical Center in Dallas has recently linked Fixodent, Super-Poligrip, and other denture creams to Hypocupremia, Low Copper - Copper deficiency is uncommon, but is sometimes found in combination with iron deficiency, especially with iron deficiency anemia. High Zinc - Exposure to high levels of zinc over long periods of time may cause adverse health effects.
Zinc Toxicity - Even though zinc is a very essential requirement for a healthy body, excess zinc can be harmful, and cause zinc toxicity. Excessive absorption of zinc can also suppress copper and iron absorption. The free zinc ion in solution is highly toxic to plants, invertebrates, and even vertebrate fish. The Free Ion Activity Model (FIAM) is well-established in the literature, and shows that just micro molar mounts of the free ion kills some organisms. A recent example showed 6 micromolar killing 93% of all Daphnia in water.
Zinc Poisoning - Zinc is a very abundant element, appearing as a bluish white metal in its pure state. Zinc is also highly adaptable and has many uses, including rust resistant coating, blending with other metals, and use in wood preservatives. A small amount of zinc is necessary for a balanced human diet. However, being exposed to more than 10 times the amount of recommended zinc can result in zinc poisoning. Zinc poisoning can be deadly if not caught and treated quickly.
High Zinc in Blood - Zinc levels are regulated by metallothionein, a short linear protein composed of 61 amino acid units. When this protein fails to perform its necessary functions, abnormal levels of nutrient metals (such as copper, zinc, and manganese) and toxic metals (such as cadmium, mercury, and lead) can result. Nutrient treatment to eliminate these overloads must be cautious and gradual to avoid worsening of symptoms and kidney damage.
Copper Supplements - Copper supplements are used to prevent or treat copper deficiency. The body needs copper for normal growth and health. For patients who are unable to get enough copper in their regular diet or who have a need for more copper, copper supplements may be necessary. They are generally taken by mouth but some patients may have to receive them by injection. Copper is needed to help your body use iron. It is also important for nerve function, bone growth, and to help your body use sugar.
Low Copper Neuropathy - Unexplained neuropathy may be the result of a copper deficiency, researchers reported at the 16th annual Meeting of the European Neurological Society. Unexplained neuropathy is a rare condition, but doctors should suspect it and measure serum copper levels in patients with myelopathy, peripheral neuropathy, or optic neuropathy.